Causes obesity, what causes obesity is caused by the

obesity is caused by what the?

etiology

calorie intake more calories to fat synthesis is the material basis of obesity.

eating calories that day than the energy consumed when required, divided by the liver and muscle glycogen in the form of storage, the almost completely converted to fat, the body fat stored in the library, mainly as triglycerides, glycogen reserves limited, the body fat is the main storage form of energy, such as regular excessive intake of neutral fat and carbohydrate, fat synthesis is to accelerate, as the external causes of obesity, often in the case of too little activity, such as stop sports exercise, reducing manual labor or bed rest recovering from disease, obesity, post-natal recuperation, etc. appear, and in normal circumstances, the body each day into the difference between calories, depending on age, gender, height, nature of work and other factors, the normal nerve Endocrine regulation of precision, so that body weight is relatively stable without the risk of obesity.

obesity accounted for 95% of obese people, usually called the [middle-aged obesity] also belongs to obesity, but obesity among middle-aged sex, sometimes hidden symptoms of obesity, it can not be ignored .

most peoples daily diet, regular intake of high calorie foods containing fat, once the excessive intake of fat, of course, will result in excess energy, while promoting fat accumulation, but also because of the excessive intake of "alcohol", which leads to energy surplus, this is a lot of people ignore, so often hear people say: [Why do I eat very little, still fat, I love to drink it,] So, the daily diet is very important The following are the reasons for the formation of overweight and obesity:

1. Genetic factors: mostly identified as [Multifactorial inheritance], the genetic constitution of parents to their children, is not from a genetic factor, but by the majority of genetic factors to determine the childs body, so called multi-factor genetic, such as non-insulin-dependent diabetes, obesity, was part of this genetic parents have an obese, the obese children, 40% chance, if both parents are obese, obese children may increase the chances to 70% ─ 80 % true because [Multifactorial inheritance] examples of rare, genetic parents [wrong eating habits], which led to the example of obesity, is common.

2. social environment factors: Many people have a [eat is a blessing] the concept of modern society, a wide range of food, variety of food often entice you, together with [a meal] is almost become a popular entertainment, of course, become the main cause of obesity.

3. psychological factors: the trouble to lift the mood, emotional instability, many people also use the [food] to make vent, this is a result of obesity caused by overeating causes.

4. and exercise-related factors: exercise helps burn fat in our daily life, with well-developed transport, mechanization of work, reduce the amount of housework, etc., making the body the opportunity to consume fewer calories, and the other area because of the energy intake did not decrease the formation of fat, fat, leading to daily activities become increasingly slow, lazy, but once again reduce the calorie consumption, leading to a vicious cycle, contributing to obesity.

pathogenesis

pathogenesis of obesity can be grouped into the following four factors:

one, because the bodys inherent factors in fat metabolism disorder caused obesity.

1, genetic factors, the incidence of obese humans have a certain genetic background, human obesity is generally considered to be more genetic, genetic disease in their play the role of a prone, obesity is still formation of behavior and life way, feeding behavior, habits, social and psychological factors, insulin response and interactions.

2, neuropsychiatric factors exist in the human hypothalamus and feeding behavior of the two pairs of nuclei, a pair of abdominal contralateral nucleus, also known as the satiety center; another ventrolateral nucleus of the center, also known as hunger, full excitability when satiety and feeding, destroyed the appetite; excitability when hungry appetite, anorexia refuse to eat when the destruction, in a state of homeostasis under physiological conditions, the appetite regulation in the normal range and maintain normal body weight, the role of the hypothalamus at the blood-brain barrier is relatively weak, the anatomical characteristics of the blood on the biological activity in a variety of easy migration to the Department to have an impact on the feeding behavior, these factors include: glucose, free fatty acid, norepinephrine , dopamine, 5 - hydroxytryptamine, insulin, etc. In addition, psychological factors often affect the appetite, the central function of prey are subject to mental state, when the psychological stress and sympathetic activity or adrenergic nerve stimulation (especially α receptor dominant), appetite suppression; when the vagus nerve and the increase in insulin secretion, the appetite often hyperactivity.

3, hyperinsulinemia hyperinsulinemia in obesity in recent years, the pathogenesis of eye-catching, obesity and hyperinsulinemia often coexist, the causal relationship between the two needs to be further explored, but the general opinion of high blood insulin disease caused by obesity, hyperinsulinemia, obesity, insulin release by approximately 3 times normal.

insulin has a significant role in promoting the accumulation of fat in a certain sense, the monitoring can be used as factors of obesity, insulin is to promote the role of body fat increased role through the following links: ① promotion of glucose into the cells, and thus synthesis of neutral fat; ② inhibiting the use of fat in fat cells.

over-feeding and the coexistence of hyperinsulinemia and obesity is often an important factor to maintain.

4, brown adipose tissue, brown adipose tissue abnormalities were discovered only in recent years a kind of fat tissue, and mainly distributed in the subcutaneous and visceral white adipose tissue surrounding the corresponding, brown adipose tissue distribution is limited, only distributed in shoulder, the back of the neck, axillary, mediastinal and renal around the appearance of their organization was light brown, relatively small changes in cell volume.

white adipose tissue is an energy storage form, the body will be excess energy storage in the form of neutral fat, the white fat cell volume with changes in energy storage and release can be larger.

brown adipose tissue in heat production is a function of the organ, that is, when the body by ingestion or cold stimulation, fat-burning brown fat cells, to determine the bodys energy metabolism, the above two cases are commonly known that feeding induction of heat and cold-induced heat production.

thermogenic brown adipose tissue of the organization directly involved in the regulation of total body heat will distribute excess body heat to the body, so that tends to balance the body energy metabolism.

the brown adipose tissue of human obese little research, but it can be observed that some dysfunction of heat obese patients.

5, other hormones is an important factor in regulating fat metabolism, especially triglyceride synthesis and mobilization of decomposition, by hormones through the regulation of the enzyme to determine their changes in trends, in which insulin and prostaglandin E1 is for fat synthesis and inhibit the decomposition of the main hormones; catechol amines, glucagon, ACTH, MSH, TSH, GH, ADH adrenal cortex hormones and sugars to promote lipolysis and inhibition of the synthesis of hormones, such as the excessive secretion of the former , which reduce the secretion; can cause an increase in fat synthesis, decomposition occurs more than fat, this group of secondary endocrine factors and obesity more closely.

Second, external factors to eating too much and too little activity-based (described before).